Jul 30, 2018
Proper handling during the collection and processing of
specimens is crucial for producing reliable results. These
pre-analytical steps are highly vulnerable to the introduction of
experimental bias and variance, which may drastically degrade
specimen quality. Analytes are affected differently by
uncontrolled variations in specimen collection, processing, and
storage protocols.
The August 2018 issue of Clinical Chemistry includes a Review
article from the Precision Medicine and Pharmacometabolomics Task
Group of the Metabolomics Society. The authors summarize the
current variability among pre-analytical processing and biobanking
procedures for metabolomics research and provide recommendations
for best practices.